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Healthcare
Healthcare
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AI / ML driven in silico drug development
AI / ML driven in silico drug development
AI / ML driven in silico drug development
STATUS:
Current
Sibylla is a preclinical-stage company focused on developing new small molecule degraders with a novel mechanism of action for unmet medical needs. Its PPI-FIT platform, powered by computer simulations and AI/ML methods, enables the discovery and development of compounds that induce the degradation of a target protein by interfering with its folding pathway. By leveraging this innovative approach, Sibylla advances the identification and development of small molecules that act on targets involved in various types of diseases.
Sibylla is a preclinical-stage company focused on developing new small molecule degraders with a novel mechanism of action for unmet medical needs. Its PPI-FIT platform, powered by computer simulations and AI/ML methods, enables the discovery and development of compounds that induce the degradation of a target protein by interfering with its folding pathway. By leveraging this innovative approach, Sibylla advances the identification and development of small molecules that act on targets involved in various types of diseases.
(Entrepreneurs)
(Entrepreneurs)
Prof. Emiliano Biasini, Co-Founder
Giovanni Spagnolli, Co-Founder & CTO
(VI Partners)
(VI Partners)
(Fund)
(Fund)
Vi-21
Portfolio News


SEP 04, 2025
Sibylla Biotech Appoints CSO and VP of R&D to Advance PPI-FIT Technology and Pipeline of Folding Interference Small Molecules
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SEP 04, 2025
Sibylla Biotech Appoints CSO and VP of R&D to Advance PPI-FIT Technology and Pipeline of Folding Interference Small Molecules
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OCT 10, 2022
Sibylla Biotech Raises €23 Million Series A to Advance Protein Degradation by Folding Interference Pipeline and Expand Technology Platform
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OCT 10, 2022
Sibylla Biotech Raises €23 Million Series A to Advance Protein Degradation by Folding Interference Pipeline and Expand Technology Platform
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